TECHNOLOGIES FOR MONITORING AND MEASUREMENT OF DIOXIN AND DIOXIN-LIKE COMPOUNDS IN SOIL AND SEDIMENT XENOBIOTIC DETECTION SYSTEM, INC. CALUX BY XDS
A demonstration of technologies for determining the presence of dioxin and dioxin-like compounds in soil and sediment was conducted under EPA's Superfund Innovative Technology Evaluation Program in Saginaw, Michigan in April 2004. This report describes the performance evaluation of Xenobiotic Detection Systems, Inc., CALUX®by XDS. This is an aryl hydrocarbon-receptor bioassay that reports total toxicity equivalents (TEQ) of dioxins/furans and polychlorinated biphenyls. The technology results were compared to high resolution mass spectrometry (HRMS) TEQ results generated using EPA Methods 1613B and 1668A.
The CALUX® by XDS generally reported data higher than HRMS TEQD/F and total TEQ values, but were generally lower than the HRMS values for TEQPCB. The technology's estimated method detection limit was 0.53 to 0.63 pg/g TEQD/F. Results from this demonstration suggested that the XDS technology could be an effective tool to screen for samples above or below 1 pg/g for TEQD/F and total TEQ, and that it could be effective for all three types of TEQ values for results above or below 50 pg/g TEQ, particularly considering that the cost ($89,564 vs. $398,029) and the time (six weeks vs. eight months) to analyze the 209 demonstration samples were significantly less than that of the reference laboratory.
The CALUX® by XDS generally reported data higher than HRMS TEQD/F and total TEQ values, but were generally lower than the HRMS values for TEQPCB. The technology's estimated method detection limit was 0.53 to 0.63 pg/g TEQD/F. Results from this demonstration suggested that the XDS technology could be an effective tool to screen for samples above or below 1 pg/g for TEQD/F and total TEQ, and that it could be effective for all three types of TEQ values for results above or below 50 pg/g TEQ, particularly considering that the cost ($89,564 vs. $398,029) and the time (six weeks vs. eight months) to analyze the 209 demonstration samples were significantly less than that of the reference laboratory.