IRIS Toxicological Review of 2,2',4,4'-Tetrabromodiphenyl Ether (External Review Draft)
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Abstract
The U.S. EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessments of congeners of polybrominated diphenyl ethers (PDBEs), this review is about 2,2',4,4'-Tetrabromodiphenyl Ether, or commonly referred to as tetraBDE (BDE-47). Following the external peer review this assessment will appear in the Integrated Risk Information System (IRIS) database. Peer review will ensure that science is used credibly and appropriately in derivation of the dose-response assessments and toxicological characterization.Impact/Purpose
EPA is updating the Integrated Risk Information System (IRIS) health assessments for the PBDEs.Citation
U.S. EPA. IRIS Toxicological Review of 2,2',4,4'-Tetrabromodiphenyl Ether (External Review Draft). U.S. Environmental Protection Agency, Washington, DC, 2007.History/Chronology
Additional Information
EPA is hereby providing for public information the draft Toxicological Review of Tetrabromodiphenyl Ether (BDE-47), and a charge to external peer reviewers for EPA's health assessment of the polybrominated diphenyl ethers. This documents is provided for public viewing and comment. Public comments received on the Toxicological Review prior to February 5, 2007 will be provided to the external peer reviewers for their consideration. Any comments received by February 16, 2007 will be considered by EPA in subsequent drafts. Please direct any correspondence, identifying the IRIS program, chemical substances, document date, and ID EPA-HQ-ORD-2006-0838 to the contact listed above.Download(s)
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.
- 2,2',4,4'-TETRABROMODIPHENYL ETHER (NCEA-S-2537) (PDF) (66 pp, 304.7 KB, about PDF)