IRIS Toxicological Review of Vanadium Pentoxide (Interagency Science Consultation Draft)
Alert
Notice - This site contains archived material(s)
Archive disclaimer
Archived files are provided for reference purposes only.
The file was current when produced, but is no longer maintained and may now be outdated.
Persons with disabilities having difficulty accessing archived files may contact the Risk Webmaster for assistance.
Please use the contact us form if you need additional support.
Abstract
On September 30, 2011, the draft Toxicological Review of Vanadium Pentoxide and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public release. In the new IRIS process (May 2009), introduced by the EPA Administrator, all written comments on IRIS assessments submitted by other federal agencies and White House Offices will be made publicly available. Accordingly, interagency comments and the interagency science consultation draft of the IRIS Toxicological Review of Vanadium Pentoxide and the charge to external peer reviewers are posted on this site.Vanadium pentoxide is the most common commercial form of vanadium. It is used as a catalyst in the production of sulfuric acid and some nanomaterials. When fuel oils containing vanadium are combusted, they leave behind byproducts containing vanadium pentoxide in the forms of dust, soot, boiler scale, and fly ash. Vanadium is found at multiple Superfund sites.
Impact/Purpose
EPA is reassessing its IRIS toxicological review of vanadium pentoxide (CASRN 1314-62-1). This vanadium pentoxide reassessment consists of an oral reference dose (RfD), an inhalation reference concentration (RfC), an inhalation unit risk (IUR) and a cancer weight of evidence descriptor. This is the first assessment developing an RfC or IUR for this compound. This assessment is intended to provide human health data to support agency regulatory decisions.Status
Following external peer review and public comment, the assessment will be revised taking into consideration the comments received. It will then undergo a final internal review by EPA and other federal agencies and White House offices. After completing the review it will be posted to the IRIS database.Citation
U.S. EPA. IRIS Toxicological Review of Vanadium Pentoxide (Interagency Science Consultation Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-11/004C, 2011.History/Chronology
| Date | Description |
|---|---|
| 01- Jan 1987 | The RfD for vanadium pentoxide was posted to the IRIS Database. |
| 03- Sep 2011 | EPA hosted an interagency science consultation on the review of the draft Toxicological Review of Vanadium Pentoxide. |
| 04- Sep 2011 | EPA released the external review draft of the vanadium pentoxide assessment for public review and comment. [Federal Register Notice Sep 30, 2011] |
Download(s)
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.
- IRIS Toxicological Review of Vanadium Pentoxide (Interagency Science Consultation Draft) (PDF) (218 pp, 1.0 MB, about PDF)
- draft Charge to External Peer Reviewers (Interagency Science Consultation draft) (PDF) (3 pp, 14.6 KB, about PDF)
- EPA's Response and Comments from the Interagency Science Consultation (PDF) (7 pp, 30.3 KB, about PDF)
- 1. CDC ATSDR vanadium pentoxide IASC comments (PDF) (1 pp, 18.6 KB, about PDF)
- 2. NIEHS NTP vanadium pentoxide IASC comments (PDF) (2 pp, 31.2 KB, about PDF)