Provisional Peer-Reviewed Toxicity Values for Perfluorobutane Sulfonic Acid (PFBS) and Related Compound Potassium Perfluorobutane Sulfonate
Provisional Peer-Reviewed Toxicity Value (PPRTV) assessments support the EPA mission to protect human health and the environment by identifying and characterizing the health hazards of chemicals of concern to the Superfund and RCRA Programs, and providing an important source of toxicity information and toxicity values for such chemicals. PPRTVs [provisional oral reference doses (p-RfDs), inhalation reference concentrations (p-RfCs), cancer risk values, and screening values] are derived after a review of the relevant scientific literature and using Agency methodologies, practices, and guidance for the development of toxicity values. Other EPA programs or external parties who choose of their own initiative to use PPRTV values are advised that Superfund resources will not be used to respond to challenges of these PPRTVs used in a context outside of the EPA Superfund Program.
Impact/Purpose
Provisional Peer-Reviewed Toxicity Values (PPRTV) assessments are developed for use by the Agency’s Office of Land and Emergency Management (OLEM) to support informed decisions in the Superfund program and at hazardous waste sites.Citation
U.S. EPA. Provisional Peer-Reviewed Toxicity Values for Perfluorobutane Sulfonic Acid (PFBS) and Related Compound Potassium Perfluorobutane Sulfonate. U.S. Environmental Protection Agency, Washington, DC, EPA/690/R-21/001F, 2021.History/Chronology
| Date | Description |
|---|---|
| 01- Jun 2018 | EPA conducted an independent external peer review of the draft report. |
| 02- Nov 2018 | EPA released the draft document, Human Health Toxicity Values for Perfluorobutane Sulfonic Acid and Related Compound Potassium Perfluorobutane Sulfonate (Public Comment Draft) for a 60-day public comment period. |
| 03- Oct 2020 | EPA conducted an independent external peer review of the draft report. |
| 05- Apr 2021 | EPA released the final report and values on the PPRTV website. Subchronic and chronic RfDs were derived. The 2014 PPRTV assessment for PFBS was archived. |
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This document has been reviewed in accordance with U.S. Environmental Protection Agency policy and approved for publication. Mention of trade names or commercial products does not constitute endorsement or recommendation for use.