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IRIS Toxicological Review of Perfluorohexanoic Acid (PFHxA) and Related Salts (External Review Draft)

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Abstract

EPA will be developing an Integrated Risk Information System (IRIS) assessment of Perfluorohexanoic Acid (PFHxA) and Related Compounds Ammonium and Sodium Perfluorohexanoate with an external review draft assessment for public comment and external peer review. When final, the assessment will appear on the IRIS database.
Perfulorohexanoic Acid and Ammonium and Sodium Perfluorohexanoate are members of the group of polyfluoroalkyl substances (PFAS). Concerns about PFHxA and other PFAS stem from the resistance of these compounds to hydrolysis, photolysis, and biodegradation, which leads to their persistence in the environment.

Impact/Purpose

Perfulorohexanoic Acid and Ammonium and Sodium Perfluorohexanoate are members of the group of polyfluoroalkyl substances (PFAS). Concerns about PFHxA and other PFAS stem from the resistance of these compounds to hydrolysis, photolysis, and biodegradation, which leads to their persistence in the environment.

Download(s)

  • IRIS TOXICOLOGICAL REVIEW OF PERFLUOROHEXANOIC ACID (PFHXA) AND RELATED SALTS (PUBLIC COMMENT AND EXTERNAL REVIEW DRAFT, FEB 2022) (PDF) (PDF)  (196  pp, 3.8 MB, about PDF)
  • EXTERNAL PANEL PEER REVIEW OF EPA'S DRAFT IRIS TOXICOLOGICAL REVIEW OF PERFLUOROHEXANOIC ACID (PFHXA) AND RELATED SALTS (FINAL PEER REVIEW REPORT) (PDF) (PDF)  (155  pp, 195.3 KB, about PDF)
  • DRAFT EXTERNAL PEER REVIEW CHARGE QUESTIONS FOR THE IRIS TOXICOLOGICAL REVIEW OF PERFLUOROHEXANOIC ACID AND RELATED SALTS (PDF) (PDF)  (5  pp, 187.5 KB, about PDF)
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Last updated on February 12, 2025
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