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Considering Complexities: Impacts of Multicellularity, Inter-Individual Variability, and Dosing on Modeling Inhaled Chemical Exposure Effects In Vitro#

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•Advances in molecular biology and biotechnology will pave the way to major improvements in the evaluation of health risks. •“These advances would make toxicity testing quicker, less expensive, and more directly relevant to human exposures. They could also reduce the need for animal testing by substituting more laboratory tests based on human cells”

Impact/Purpose

Presentation on data regarding the impact of multi-cellular co-culture, inter-individual variability, and dosing methods on in vitro systems used for the assessment of inhalable materials.

Citation

McCullough, S. Considering Complexities: Impacts of Multicellularity, Inter-Individual Variability, and Dosing on Modeling Inhaled Chemical Exposure Effects In Vitro#. Research Institute for Fragrance Materials Respiratory Working Group, Virtual, NC, February 15, 2023.
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Last updated on April 01, 2023
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