IRIS Toxicological Review of Diisobutyl Phthalate (Dibp) (Preliminary Assessment Materials)
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Abstract
In September 2014, EPA released the draft literature searches and associated search strategies, evidence tables, and exposure response arrays for DIBP to obtain input from stakeholders and the public prior to developing the draft IRIS assessment. Specifically, EPA was interested in comments on the following:- Draft literature search strategies
- The approach for identifying studies
- The screening process for selecting pertinent studies
- The resulting list of pertinent studies
- Preliminary evidence tables
- The process for selecting studies to include in evidence tables
- The quality of the studies in the evidence tables
Impact/Purpose
The purpose of this document is to distribute preliminary materials for diisobutyl phthalate (DIBP). This information is distributed solely for the purpose of pre-dissemination review under applicable information quality guidelines. These preliminary materials include a planning and scoping summary, information on the approaches used to identify pertinent literature, results of the literature search, approaches for selection of studies for hazard identification, presentation of critical studies in evidence tables and exposure-response arrays, and mechanistic information for DIBP. These preliminary materials are being circulated for review of its technical accuracy and science policy implications. These materials will be posted on the EPA website to make them available to the public.Citation
U.S. EPA. IRIS Toxicological Review of Diisobutyl Phthalate (Dibp) (Preliminary Assessment Materials). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-14/333, 2014.History/Chronology
Download(s)
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.
- Scoping Information, Preliminary Literature Search, Associated Strategy and Evidence Tables for DIBP (PDF) (152 pp, 1.9 MB, about PDF)
- DIBP Errata Sheet (PDF) (1 pp, 366.2 KB, about PDF)
- Primary literature search references sorted by author (DIBP) (dynamic literature link - generated by HERO, leaving the IRIS website)
- Literature selection process for the DIBP primary literature (dynamic literature link - generated by HERO, leaving the IRIS website)
- Mechanistic table (DIBP) (dynamic literature link - generated by HERO, leaving the IRIS website)
- Targeted literature search for epidemiological references sorted by author (phthalate) (dynamic literature link - generated by HERO, leaving the IRIS website)
- Literature selection process for the DIBP targeted epidemiological literature (dynamic literature link - generated by HERO, leaving the IRIS website)
- IRIS February 2015 Public Science Meeting & Presentations