Human Health Toxicity Values for Perfluorobutane Sulfonic Acid and Related Compound Potassium Perfluorobutane Sulfonate (Public Comment Draft, 2018)
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Abstract
EPA announced the availability of the draft report, Human Health Toxicity Values for Perfluorobutane Sulfonic Acid (CASRN 375-73-5)and Related Compound Potassium Perfluorobutane Sulfonate (CASRN 29420-49-3) for public review and comment as announced in a November 21, 2018 Federal Register Notice.Included in the report were draft subchronic and chronic oral toxicity values for perfluorobutane sulfonic acid (PFBS) and its related salt, potassium perfluorobutane sulfonate (K+PFBS). The toxicity assessment for PFBS is a scientific and technical report that includes toxicity values associated with potential noncancer health effects following oral exposure (in this case, oral reference doses [RfDs]). This assessment evaluates human health hazards. The toxicity assessment and the values contained within is not a risk assessment as it does not include an exposure assessment nor an overall risk characterization. Further, the toxicity assessment does not address the legal, political, social,economic, or technical considerations involved in risk management. When final, the PFBS toxicity assessment can be used by EPA, states, tribes, and local communities, along with specific exposure and other relevant information, to determine, under the appropriate regulations and statutes, if, and when, it is necessary to take action to address potential risk associated with human exposures to PFBS.
Impact/Purpose
The EPA is issuing developmental, subchronic and chronic toxicity values (RfDs) for perfluorobutane sulfonic acid (PFBS), CASRN 375-73-5, and its related salt potassium perfluorobutane sulfonate (K+PFBS), CASRN 29420-49-3. EPA is publishing these toxicity values as tools for our State, Tribal, and EPA Program/Regional partners to use in addressing contamination concerns in a variety of exposure scenarios.Citation
U.S. EPA. Human Health Toxicity Values for Perfluorobutane Sulfonic Acid and Related Compound Potassium Perfluorobutane Sulfonate (Public Comment Draft, 2018). U.S. Environmental Protection Agency, Washington, DC, EPA/823/R-18/307, 2018.History/Chronology
| Date | Description |
|---|---|
| 01- Jun 2018 | EPA conducted an independent external peer review by letter of the draft report. |
| 02- Nov 2018 | EPA released the draft document, Human Health Toxicity Values for Perfluorobutane Sulfonic Acid and Related Compound Potassium Perfluorobutane Sulfonate (Public Comment Draft) for a 60-day public comment period. |
Download(s)
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.
- Human Health Toxicity Values for Perfluorobutane Sulfonic Acid and Related Compound Potassium Perfluorobutane Sulfonate (Public Comment Draft) (PDF) (151 pp, 6.2 MB, about PDF)
- News Release: Nov 14, 2018
- Fact Sheet: PFBS Human Toxicity (PDF) (6 pp, 558.6 KB, about PDF)
- Technical Fact Sheet: Draft Assessment for PFBS (PDF) (9 pp, 727.5 KB, about PDF)
- EPA Response to Peer Review Comments on the 2018 Draft Report (PDF) (68 pp, 562.5 KB, about PDF)
- HERO: Collected scientific literature on PFBS toxicity