Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock ( Lock A locked padlock ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

  • Environmental Topics
  • Laws & Regulations
  • Report a Violation
  • About EPA
Risk Assessment
Contact Us

Human population density and reproductive health: a changing world needs endocrinology

On this page:

  • Overview
  • Downloads
Many animal species, from insects to elephants, show reduced rates of reproduction when population density is high, an effect that is often mediated by the stress axis. A recent review in the journal Endocrinology, titled “Population numbers and reproductive health,” suggests this density-dependent reproduction could also be occuring in humans, contributing to the observed global decline in fertility. In this invited commentary, we explore this hypothesis further and suggest ways in which it could be tested. For example, defining population density as social interactions per unit time, rather than by the number of individuals per unit area, could allow many confounding factors to be untangled. In addition, we suggest that a further examination of how and where density is encoded in the brain could advance our understanding of the interaction between population density, social interactions, and reproductive physiology. Adequately testing the hypothesis put forward is important. The outcome has the potential to yield novel insight into causes of infertility, as well as implications for modeling and planning for changes in population growth.

Impact/Purpose

Many animal species, from insects to elephants, show reduced rates of reproduction when population density is high, an effect that is often mediated by the stress axis. A recent review in the journal Endocrinology, titled “Population numbers and reproductive health,” suggests this density-dependent reproduction could also be occuring in humans, contributing to the observed global decline in fertility. In this invited commentary, we explore this hypothesis further and suggest ways in which it could be tested. For example, defining population density as social interactions per unit time, rather than by the number of individuals per unit area, could allow many confounding factors to be untangled. In addition, we suggest that a further examination of how and where density is encoded in the brain could advance our understanding of the interaction between population density, social interactions, and reproductive physiology. Adequately testing the hypothesis put forward is important. The outcome has the potential to yield novel insight into causes of infertility, as well as implications for modeling and planning for changes in population growth.

Citation

Weitekamp, C. AND H. Hofmann. Human population density and reproductive health: a changing world needs endocrinology. Endocrine Society, 162(12):1-3, (2021). [DOI: 10.1210/endocr/bqab198]

Download(s)

DOI: Human population density and reproductive health: a changing world needs endocrinology
  • Risk Assessment Home
  • About Risk Assessment
  • Risk Recent Additions
  • Human Health Risk Assessment
  • Ecological Risk Assessment
  • Risk Advanced Search
    • Risk Publications
  • Risk Assessment Guidance
  • Risk Tools and Databases
  • Superfund Risk Assessment
  • Where you live
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on October 15, 2021
United States Environmental Protection Agency

Discover.

  • Accessibility Statement
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshots
  • Grants
  • No FEAR Act Data
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data
  • Inspector General
  • Jobs
  • Newsroom
  • Open Government
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions

Follow.