Enriched housing alters cardiovascular function in male and female ApoE -/- mice and responsiveness to eucalyptus wildfire smoke

This study showed that housing enrichment blunts the development of atherosclerosis effects in male and female mice and subsequent deleterious responses to wildfire smoke. 

Impact/Purpose

This study examined the impact of living conditions on the cardiovascular function of male and female atherosclerosis-prone mice and subsequent responses to eucalyptus wildfire smoke. The goal of this work was to determine if non-environmental stressors increase risk and the degree of resiliency conferred by housing enrichment. 

Citation

Toler, S., M. Fiamingo, K. Lee, W. Oshiro, Todd Krantz, P. Evansky, D. Davies, Ian Gilmour, A. Farraj, AND M. Hazari. Enriched housing alters cardiovascular function in male and female ApoE -/- mice and responsiveness to eucalyptus wildfire smoke. Society of Toxicology, San Diego, California, March 27 - 31, 2022.