Development of an aerosol compatible cell culture exposure system and its application to quantify cellular uptake of particles at the air liquid interface
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• Medium-throughput: 6 doses + 4 technical replicates within standard 24-well cell culture plate
• Allows Benchmark Dose (BMD) modeling to estimate in vitro Points of Departure (PODs) for portal of entry effects
• Real-time sampling allows accurate exposure conditions to be reported throughout 2 h exposure