Investigating immune responses to Harmful Algal Bloom cyanotoxins in protection of human health and the environment
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The objective of the study is to determine if available normal 3D human skin tissue culture system can be used to detect and quantify the effects of exposure to cyanobacteria in a water sample like what might be observed in skin rashes or irritations of swimmers exposed to lake waters containing cyanobacteria. Information is needed in proper management, prevention of exposure especially to vulnerable populations (young, asthmatic, immunosuppressed and especially those living near water bodies prone to HCBs and risk assessment. The results studies can be used to characterize the toxicological and immunological properties of cyanobacteria and their metabolites. The information will help interpret the results and provide a linkage between cyanobacteria, toxins, immunological response and overall health effects.