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Evaluation of Anatoxin-a Health Effects in Mice- November 2024 Update

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  • Overview
This subproduct is a presentation given as a webinar for the Office of Water harmful algal bloom series. It is an update on the progress of an anatoxin-a research project including toxicokinetics, plethysmography, and evaluating dose-response endpoints after a 5-day oral exposure of four dose levels including a vehicle control (0, 2, 4, and 6 mg/kg anatoxin). These endpoints include serum chemistry, proteomics, neurobehavioral, male reproductive, metabolomics and transcriptomics. It is being presented as a work in progress.

Impact/Purpose

The purpose is to present a work-in-progress update to EPA and stakeholders in the Regions about an anatoxin toxicology research project in ORD.

Citation

Jenkins-Hill, D., T. Jackson, AND P. Schlosser. Evaluation of Anatoxin-a Health Effects in Mice- November 2024 Update. Harmful Algal Blooms, Hypoxia, and Nutrients Research Webinar Series, Research Triangle Park, NC, November 20, 2024.
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Last updated on November 22, 2024
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