Thyroid Disruption, Chemical Pollution and Nutritional Deficiencies
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Environmental chemicals can interfere with the thyroid system at numerous sites, and these are most often detected by alterations in circulating levels of thyroid hormone. There is significant public health need to provide protection of the developing brain of the fetus, newborn, and young child from thyroid system disrupting chemicals. In this presentation the effects of developmental exposure to perchlorate and iodine deficiency. Neurodevelopmental effects of perchlorate exposure are not only unmasked but greatly exacerbated under conditions of dietary iodine insufficiency, effects that would not necessarily be predicted from rodent models of either one alone.