Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock ( Lock A locked padlock ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

  • Environmental Topics
  • Laws & Regulations
  • Report a Violation
  • About EPA
Risk Assessment
Contact Us

Predicting Cyanobacteria Abundance and Microcystin Detection in 125,000 On-Network US Lakes

On this page:

  • Overview
The presence of cyanobacterial harmful algal blooms (cyanoHABs) in freshwater lakes across the United States poses a serious threat to ecosystems and human health. National-scale datasets allow for engagement with broad spatial patterns such as watershed and waterbody specific characteristics that can increase or diminish the risk of cyanoHABs. With spatially explicit regression models, we use lake morphology, watershed nutrient input, land cover, and geographic and meteorological data to predict cyanobacteria abundance and the probability of the cyanotoxin microcystin in approximately 124,500 US lakes. Approximately 62.2% of lakes were predicted to exceed a high threshold of 100,000 cyanobacterial cells/mL at least once during the summer, and 14.8% had a high probability of detectable microcystin during this same period. Many of these predictions were expected based on anthropogenic nutrient inputs. Inconsistent with our expectations, 33.5% of the high cyanobacteria predictions and 6.5% of likely microcystin detections occurred in watersheds with low nutrient inputs. Within these subsets of lakes, we investigated other drivers influencing cyanoHABs beyond anthropogenic nutrient inputs and the model covariates. Lakes with low nutrient inputs and high cyanoHAB risk were observed in watersheds with higher drainage ratios (watershed:lake area) than other lakes. In addition, lakes with higher area:depth ratios (lake surface area compared to depth) had higher cyanoHABs risk in both high and low nutrient groups, providing additional insight into the increased risk associated with shallower lakes. This research can help determine how watershed and lake characteristics, in addition to nutrient supply, may inform algal bloom mitigation efforts.

Impact/Purpose

Cyanobacterial harmful algal blooms pose a serious threat to human health and the environment by compromising the water quality of lakes across the United States. Cyanotoxins such as microcystin can result in serious illness in humans and ecological damage to the waterbody. This work presents modeled predictions of cyanobacterial abundance and probability of microcystin detection for 124,500 lakes across the lower 48 states. This work will help inform bloom mitigation efforts by identifying characteristics, in addition to nutrient supply, of waterbodies that develop harmful algal blooms. The work described here will be presented at the EPA's HABs, Hypoxia and Nutrients webinar September 2025. The symposium audience consists of students, professors, and industry professionals. This conference will allow for national collaboration, promoting the applications of EPA tools and research, interdisciplinary water quality solutions, and knowledge sharing.

Citation

Reynolds, M., A. Handler, M. Dumelle, J. Compton, L. Jansen, M. Weber, M. Brehob, R. Sabo, M. Pennino, AND R. Hill. Predicting Cyanobacteria Abundance and Microcystin Detection in 125,000 On-Network US Lakes. HABs, Hypoxia, and Nutrients Research Webinar Series, Virtual, OR, September 24, 2025.
  • Risk Assessment Home
  • About Risk Assessment
  • Risk Recent Additions
  • Human Health Risk Assessment
  • Ecological Risk Assessment
  • Risk Advanced Search
    • Risk Publications
  • Risk Assessment Guidance
  • Risk Tools and Databases
  • Superfund Risk Assessment
  • Where you live
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on September 29, 2025
United States Environmental Protection Agency

Discover.

  • Accessibility Statement
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshots
  • Grants
  • No FEAR Act Data
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data
  • Inspector General
  • Jobs
  • Newsroom
  • Open Government
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions

Follow.